Ravus Nox Fleuret, the former prince of Tenebrae, feels differently about the Lucian kings than his younger sister, Lunafreya, does.
From the video game Final Fantasy XV
Yoko Inokuma loves her little brother Kota and little sister Mitsuki, even if the young twins say they don’t like her. They’re big liars, and she knows it.
From the anime series Kiniro Mosaic (KINMOZA!)
The son and oldest child of the Enomoto household is a NEET (Not in Education, Employment, or Training) who stays home all day long, whereas the younger daughter, Yuiko, is the former president (and current vice president) of her school’s student council. She’s kind and understanding to him but hot-headed toward pretty much everyone else. When they were children, he teased her a lot, but as an adult, he’s a masochist. Really, the only thing they have in common is their long red hair.
From the anime series Love Lab
Tanaka is the laziest, most apathetic person to ever (not) walk the earth, but Rino, his much more active little sister, loves him all the same.
From the anime series Tanaka-kun wa Itsumo Kedaruge (Tanaka-kun is Always Listless)
Jun Furuya is idolized by his little sister, Hotaru. As such, she is extremely possessive of him and aggressive toward any girl who tries to get close to him.
From the anime series Tsurezure Children (Tsuredure Children)
Shoutarou Torii and his little sister, Moa, do not get along. He finds her rude and mean most of the time, especially when she calls him “baldy”, while she considers him to be loud, annoying, and shamelessly perverted. That said, he won’t hesitate to protect her if she’s in trouble.
From the anime series Saikin, Imouto no Yousu ga Chotto Okashiinda ga. (Recently, My Sister is Unusual)
Sorata Kanda lives in a co-ed dormitory with many pretty girls, much to the dismay of his possessive and adoring little sister, Yuuko.
From the anime series Sakurasou no Pet na Kanojo (The Pet Girl of Sakurasou)
Akuru Akutsu loves doing two things: doting on his little sister, Ruri, and studying for school.
From the anime series Aho-Girl
Hazuki Yazakura has a different last name than her younger brother, Chitose Hitotose, and younger sister, Minazuki Rokumatsuri, because they’re orphans who became self-adopted siblings.
From the anime series Happy Lesson
Kirino Kosaka forces her older brother, Kyosuke, to give her life counseling advice about how she can be more open about her hobbies. It also serves as a way to strengthen their bonds as siblings after years of neglect.
From the anime series Ore no Imouto ga Konnani Kawaii Wake ga Nai. (My Little Sister Can’t Be This Cute.)