Onii-chan Dakedo Ai Sae Areba Kankeinai yo ne!: Let’s Do It

Akito Himenokoji sighs as Akiko Himenokoji gives him a thumps up while holding a pillow that says Yes on it

After six years of living apart, Akito Himenokoji reunites with his little sister, Akiko, only to learn that she’s developed a complex towards him.
From the anime series Onii-chan Dakedo Ai Sae Areba Kankeinai yo ne! (OniAi)

Fantastic Four: Light and Fire (2015)

Susan Storm and Johnny Storm standing in front of a building

Adopted sister Susan Storm is sarcastic and brilliant, and her younger brother, Johnny, is a thrill-seeking troublemaker.
From the 2015 movie Fantastic Four

Dexter: Duo in the Dark

Debra and Dexter Morgan

Dexter Morgan: Blood spatter analyst for the police by day and serial killer by night.
Debra Morgan: Law enforcement officer unaware of her older brother’s murderous activities.
From the Showtime series Dexter

Image from Showtime