Alexis “Lex” Murphy is a self-described computer hacker, and her little brother, Tim, knows a lot about dinosaurs. Together, they use their skills to escape from danger when the park’s systems break down and dinosaurs run amok.
From the movie Jurassic Park
Keiichi Morisato and his little sister, Megumi, are both skilled mechanics and exceptional race drivers who go to school at the Nekomi Institute of Technology.
From the anime series Aa! Megami-sama! (Oh My Goddess!)
After the death of the king in Robert’s Rebellion, Prince Viserys Targaryen and his little sister, Princess Daenerys, fled across the Narrow Sea in exile. They hope to return to Westeros one day and reclaim their father’s throne.
From the television series, Game of Thrones, adapted from George R. R. Martin’s A Song of Ice and Fire novels
Tamotsu Denkigai and his little sister, Niwaka, are otakus who love the Akihabara shopping district, and they battle against monsters called “Bugged Ones” that are trying to destroy it.
From the anime series Akiba’s Trip: The Animation
Touga Kiryuu is president of Ootori Academy’s student council and is popular among the school’s female population. His possessive little sister, Nanami, however, only wants him to pay attention to her and punishes any girls who try to get close to him.
From the anime series Shoujo Kakumei Utena (Revolutionary Girl Utena)